FLEX ISYNTH for Library Synthesis Small Scale

Enhanced with disposable glass reactors, SWILE for small-scale (μL) synthesis, and SMOLE, revolutionary, standardized, ready-to-apply chemicals consumables

Automated Synthesis For Innovative Medicines

Medicinal chemistry is driven more and more by the demand for innovative medicines which involves molecular diversity and novel routes, meaning more and more experiments typically with the same resources. Chemspeed’s fully automated, integrated FLEX ISYNTH stands for a flexible, modular, and uncompromising automated solution that:

  • Unlocks the chemical space via faster, better, virtually unrestricted “off-road” chemistry investigation of the reaction, reagent and molecule space.
  • Enhances your efficiency and productivity by a factor of up to 100 in e.g.:
    • C-C, C-N coupling reactions
    • Organometallic reactions (e.g. Grignard)
    • Alkylations
    • Diels-Alder reactions
    • Transfer hydrogenations

Reactor Arrays
  • Temperature control (-20 - 150°C)
  • Mixing (vortexing)
  • Automated closing / opening
  • Reaction sampling (fully automated without need for screw capping or septa piercing for fast sampling)
  • Small-scale disposable glass vials (750 μL total volume, 100+ μL reaction volume)
  • 48 parallel batch reactions (MTP)



  • Fully automated, integrated reaction preparation, synthesis, work-up, analysis, output to storage vials for solid- and liquid-phase library synthesis
  • Throughput, up to 48 parallel reactions per plate
  • Integrated liquid handling and sampling
  • Ventilated hood for safety and conditioned operation, trolley
  • Optimized footprint (3x3 ft, 90x90 cm) versus capacity... all while reducing coats / maximising return on investment