High-Throughput Library Synthesis with online NMR (e.g. automated synthesis and characterization of innovative medicines)

FLEX ISYNTH Library Synthesis with online NMR

Facing challenges like

Medicinal chemistry is driven more and more by the demand for innovative medicines which involves molecular diversity and novel routes, meaning more and more experiments typically with the same resources.

Chemspeed’s fully automated, integrated FLEX ISYNTH stands for a flexible, modular, and uncompromising automated solution that:

  • Unlocks the chemical space via faster, better, virtually unrestricted “off-road” chemistry investigation of the reaction, reagent and molecule space.
  • Enhances your efficiency and productivity by a factor of up to 100 in e.g.:
    • C-C, C-N coupling reactions
    • Organometallic reactions (e.g. Grignard)
    • Alkylations
    • Diels-Alder reactions
    • Transfer hydrogenations

Reactor arrays
  • Easy-to-use disposable multi-functional, high-precision glass reactor arrays:
    • Available reaction scales from μl to ml
    • Screwless and self-sealing opening / closing
    • Mixing by shaking (up to 600 rpm)
    • Heating (up to 150°C), cooling (-20°C)
    • Refluxing, vacuum, inertization, evaporation, extraction, filtration, crystallization and drying
  • Chemistry proven liquid handling with e.g. pH, filtration extension.
  • Proprietary robotic tool exchange for e.g. gravimetric solid handling.