The ligand, catalyst precursor and catalyst distribution from the libraries into the reaction screening plates is often still done manually and binds highly qualified resources to very time-consuming, tedious, and error-prone tasks.
The ligand, catalyst precursor and catalyst distribution from the libraries into the reaction screening plates is often still done manually and binds highly qualified resources to very time-consuming, tedious, and error-prone tasks.
The SWILE technology is the first fully automated true one-to-one gravimetric "pick & decision dispense" of catalysts. The scheme at the bottom of this page displays the simplified SWILE workflow including a precision "pick & decision dispense" step. The technology backbone is following Chemspeed’s proprietary overhead gravimetric dispensing tool design in combination with a second analytical on-deck-balance.
In order to exclude any risk of cross-contamination disposable glass tips are used which are stored and provided by a SWIN dispenser. The SWINS are available in different sizes (diameter) and can be adjusted according to the desired target amount to be dispensed. Additionally, a tilt / shake rack is used to loosening up and tilt the powder prior to pick-up.