Pharmaceutical industry faces the increased demand for innovative medicines against various diseases. In this regard, the compound library in pharmaceutical industry is the most valuable asset. However, the compound distribution from the library into the screening plates is often still done manually and binds highly qualified resources to very time-consuming, tedious, and error-prone tasks.
The SWILE technology is the first fully automated true one-to-one gravimetric "pick & decision dispense" of compounds. The scheme at the bottom of this page displays the simplified SWILE workflow including a precision "pick & decision dispense" step. The technology backbone is following Chemspeed’s proprietary overhead gravimetric dispensing tool design in combination with a second analytical on-deck-balance.
In order to exclude any risk of cross-contamination disposable glass tips are used which are stored and provided by a SWIN dispenser. The SWINS are available in different sizes (diameter) and can be adjusted according to the desired target amount to be dispensed. Additionally, a tilt / shake rack is used to loosening up and tilt the powder prior to pick-up.