Automated Gravimetric Pick & Decision Dispense of Honey-like Compounds - Step Change in Compound Management


FLEX SWIP

Pharmaceutical industry faces the increased demand for innovative medicines against various diseases. In this regard, the compound library in pharmaceutical industry is the most valuable asset. However, the compound distribution from the library into the screening plates is often still done manually and binds highly qualified resources to very time-consuming, tedious, and error-prone tasks.

 

Tools

The SWIP technology is the first fully automated true one-to-one gravimetric "pick & decision dispense" of honey-like compounds. The scheme at the bottom of this page displays the simplified SWIP workflow including a precision "pick & decision dispense" step. The technology backbone is following Chemspeed’s proprietary overhead gravimetric dispensing tool design.

Dispensing Characteristics

  • Revolutionary accuracy & precision due to decision dispensing.
  • Dispensing range from <100 μg to 100 mg with +/- 10 μg resolution.
  • No cross-contamination.
  • No dead volume.
  • Unattended operation.
  • Fully inert (glass).

In order to exclude any risk of cross-contamination disposable glass tips (SWIPs) are used which are stored and provided by a SWIP dispenser. 

The SWIP are available in different sizes (diameter) and can be selected according to the desired target amount to be dispensed. 

Pick & Decision Dispense
Platform

  • Proprietary robotic tool exchange interface.
  • Ventilated hood for safety and conditioned operation, trolley.
  • Optimized footprint (3x3 ft, 90x90 cm) versus capacity - all while reducing costs and maximizing return on investment.
  • AutoSuite Software - drag & drop experimentation with easy interface to DoE and data analysis.
  • Application programming interface for e.g. LIMS, ELN integration.
  • SWIP Robotic Tool can be combined with other tools to accommodate multiple workflows.
  • SWILE, tilt / shake rack, barcode reader.

AutoSuite Software

The intuitive and easy to use software supports the fully unattended production of screening assays from the pharmaceutical compound library.

Combination of SWIP / SWILE

SWILE : "pick & decision dispense" of solids in the range from <100 μg to 100 mg.