Screening at Elevated pressures (1-100 bar) in up to 96 wells


The ISYNTH SPEEDCHEM uses a combination of elevated temperature and pressure to increase the reaction rate, resulting in shorter reaction times and higher selectivities.


  • Decrease in cost per experiment up to 90+ %.
  • Increase in productivity by a factor of 10+.
  • Increased temperature to e.g. 40°C above the boiling point results in about 16 times faster reaction at better quality.
  • Reagent preparation (liquids and solids), multistep synthesis, work-up, purification, analysis and product transfer to storage.
  • Disposable glass reactors in MTP format.
  • 4-Needle Head for volumetric liquid handling and sampling.
  • Gravimetric solid dispensing into an unlimited choice of vial / plate / reactor formats.
  • Higher reagents solubility into solvent.
  • Milder reaction conditions.
  • Less side reactions / reagent alteration and higherchemical yield.
  • Lower energy usage.
  • Exchangeable robotic tools to accommodate multiple workflows.
  • Easy access to data with a convenient interface to pull results into Excel or virtually any other software.
  • Interface to DOE.

Enhance your Efficiency and Productivity with our Workflow Solutions!

ISYNTH SPEEDCHEM workflow for automated SPE

Do it in the microwave “way”, but 96 instead of 1 at a time and at faster reaction rates.

As a rule of thumb the reaction rate doubles itself if the temperature is increased by 10°C, reactions that normally take hours can be done in minutes at better quality using ISYNTH SPEEDCHEM.

Selection of application:

  • Library synthesis.
  • Porous material synthesis .
  • Polymer synthesis.
  • Reaction parameter screening.
  • Solubility, stability, compatibility screening.
  • Sample preparation.
  • Formulation screening.

Fully automated well-plate (pressure) screening block

Pick-up metallic MTP with 96 glass vials

Pick-up metallic MTP with e.g. 96 glass vials

Transfer plate to pressure block

Transfer plate

automated process research under pressurized conditions

Load plate into pressure block

MTP (well-plate) pressure block with screwless, self-sealing automated opening / closing

MTP (well-plate) pressure block with screwless, self-sealing automated opening / closing

Customer testimonial

“Do it in the microwave “way”! But 96 instead of 1 at a time and at faster reaction rates.”