Paradigm Shift – Combination of Batch & Flowchemistry


Paradigm Shift – Combination of Batch & Flowchemistry

The leading technology in versatile comibnation of batch & flowchemistry combined with our reactor and process excellence, and our user-friendly software, allow you to standardize and accelerate your organic process R&D workflows.

Key Advantages:

  • Decrease in cost per experiment up to 90+ %.
  • Increase in productivity by a factor of 10+.
  • Up to 36 experiments per run on an autoplant, up to 12 experiments per run on a FLEX.
  • Combination of batch & flowchemistry.
  • Independent and precise process parameter control in each reactor (such as feed / flow, temperature, mixing).
  • Independent gas, liquefied gas and liquid feeds.
  • Gravimetric solid and (viscous) liquid dispensing.
  • 4-Needle Head for volumetric liquid handling and sampling.
  • PAT like IR, PSD, calorimetry, pH.
  • Feeding and sampling under reaction conditions.
  • Reaction under reflux at ambient pressure with optional Dean Stark water removal or distillation.
  • Reactions at elevated pressure.
  • Vessel-to-vessel transfer for multistep reactions.
  • Workup with liquid / liquid extraction, drying, solid-phase extraction, filtration or evaporation.
  • Cleaning in place (e.g. automated cleaning, inserts).
  • Dispensed amount, stirrer speed, temperature, pressure, time…, and other data are stored in a read only log file.
  • Easy access to data with a convenient interface to pull results into Excel or virtually any other software.
  • Interface to DoE.

Enhance your Efficiency and Productivity with our Workflow Solutions!

Example FLOWCHEM Configurations