Automated Catalyst Testing & Process Development

Decrease in cost per experiment up to 90+ %.
Increase in productivity by a factor of 10+.
Up to 36 experiments per run on an autoplant, up to 6 experiments per run on a multiplant.
Independent control of all process parameters in each reactor with PAT like NIR, PSD, calorimetry, pH.
Independent and precise temperature and stirring control in each reactor.
Up to 8 independent gas, liquefied gas and liquid feeds per reactor.
Gravimetric solid and viscous liquid dispensing.
4-Needle Head for volumetric liquid handling and sampling.
Feeding and sampling under reaction conditions.
Reaction under reflux at ambient or elevated pressure with optional Dean Stark water removal or distillation.
pH monitoring and control.
Vessel-to-vessel transfer for multistep reactions.
Workup with liquid / liquid extraction, drying, solid-phase extraction, filtration or evaporation.
Cleaning in place (e.g. automated cleaning, inserts).
Dispensed amount, stirrer speed, temperature, pressure, time and other data are stored in a read only log file.
Easy access to data with a convenient interface to pull results into Excel or virtually any other software.
Interface to DoE.

Enhance your Efficiency and Productivity with our Workflow Solutions!

MULTIPLANT AUTOPLANT PRORES workflow for automated process research

Assembly of a process research reactor with our unique screwless and self-sealing design up to 100 bar

Process Research Reactor Assembly

Customer testimonial

“The AUTOPLANT PRORES paid for itself within less than 12 month”

Chemspeed’s MULTIPLANT/ AUTOPLANT PRORES deck modularity allows the user to execute and perform a variety of workflows in a fully or semi-automated fashion.

The synthesis of most organic compounds includes the following steps which can all be fully automated on the MULTIPLANT / AUTOPLANT PRORES:

Interface to DoE.
Addition of liquid and / or solid reagents.
Reaction under reflux at ambient or elevated pressure with optional Dean Stark water removal or distillation.
pH monitoring and control.

Vessel-to-vessel transfer for multistep reactions.
Work-up with liquid / liquid extraction, drying, solid-phase extraction, filtration or evaporation.
Product isolation.
Analysis.

Process development workstation for 6 X 100 mL, 3 X 250 mL, 3 X 1’000 mL

The cutting edge Process Development Workstation Technology allows scientists to truly mimic the final industrial production process and provides all the flexibility to optimize integrated reaction sequences, even if a complex configuration of reactors and feed vessels required.

Process development reactors in glass, stainless steel or hastelloy

Materials of choice: glass, stainless steel (PEEK, PTFE or glass inserts available), Hastelloy, others on request

Process reactor assembly, individually controlled tank reactors (reactor volumes 100, 250, 1’000 mL) with precise, continuous feeds.

Flexible and precise continuous feeds, down to 10 μL / min.
Up to 8 continuous liquid, liquefied gas and / or gas feeds per reactor and additional unlimited overhead access.
Accurate and reproducible temperature control, 0.1 °C.
Pressure up to 100 bar over the entire temperature range up to 250 °C with corresponding safety installations.
Parallel high-performance calorimetry NIR, PSD, pH data.
Viscosity data.
Dean Stark water trap.
Distillation bridge between 2 reactors.

anchor, twisted blade and gas entrainment stirrers (exchangable)

Easily exchangeable stirrer designs (anchor, twisted blade, gas entrainment stirrers…). Powerful mixing for viscosities up to 80 Pa.s at 300 rpm and 30 Pa.s at 900 rpm with an anchor stirrer.

Flexible Configuration

For one single unit, various feeding modes are available: batch, semi-continuous, continuous, continuous cascade.