Quality by Design (QbD), Proven Accetable Range (PAR) Driven Automated Process R&D and Preparative Synthesis Solutions (for organics, inorganics, polymers)


MULTIPLANT / AUTOPLANT

Robustness and ease-of-use by design - Each reactor with its own set of conditions

The leading technology in overhead gravimetric dispensing / dosing (patented) combined with our quality by design reactor technologs and process excellence, and our user-friendly software, allow you to accelerate, standardize and digitalize your process / chemical development workflows (reaction preparation, synthesis, work-up, analysis).

Key advantages

  • Decrease in cost per experiment up to 90+ %.
  • Increase in productivity by a factor of 10+.
  • Up to 36 experiments per run on an AUTOPLANT, up to 6 experiments per run on a MULTIPLANT.
  • Independent control of all process parameters in each reactor with calorimetry and e.g. NIR, PSD, pH.
  • Independent and precise temperature and stirring control in each reactor.
  • Up to 8 independent gas, liquefied gas and liquid feeds per reactor.
  • Gravimetric solid and viscous liquid dispensing.
  • 4-Needle Head for volumetric liquid handling and sampling.
  • Feeding and sampling under reaction conditions.
  • Cleaning in place (e.g. automated cleaning, inserts).
  • Dispensed amount, stirrer speed, temperature, pressure, time..., and other data are stored in a read only log file.
  • Easy access to data with a convenient interface to pull results into Excel or virtually any other software.
  • Interface to DOE.

Enhance your efficiency and productivity with our workflow solutions!

  • Organic synthesis & scale-up.
  • Crystallization.
  • Ligand synthesis & scale-up.
  • Organometallic synthesis & scale-up.
  • Ziegler-Natta synthesis.
  • Polyolefin prepolymerizations, solution-, slurry-, bulk-, gas-phase, multi-stage syntheses.
  • Living / controlled, emulsion, suspension, mass polymerizations.
  • Impregnations.
  • (Mixed) oxide, zeolite syntheses.
  • Catalyst testing in batch, semi-continuous, continuous mode.
  • Nanomaterials syntheses.
  • Biomass pretreatment and conversion.

 

With individual sets of conditions for each reactor!

Assembly of a process research reactor with our unique screwless and self-sealing design up to 100 bar
Technical details

Chemspeed’s MULTIPLANT / AUTOPLANT deck modularity allows the user to execute and  perform a variety of workflows in a fully or semi-automated fashion.

The Chemspeed MULTIPLANT / AUTOPLANT workstations have been designed for high output experimentation in the development and optimization of pharmaceuticals, agrochemicals, polymers, specialty chemicals, catalysts and many more.

  • Process R&D.
  • Organic and inorganic synthesis, reactions under pressure (process research, optimization and scale-up).
  • Preparative synthesis.
  • Validation.
  • Polymersynthesis (mass-, solution-, pressure-, emulsion-polymerization).
  • Crystallization.

The cutting edge Process Development Workstation Technology allows scientists to truly mimic
the final industrial production process and provides all the flexibility to optimize integrated reaction sequences, even if a complex configuration of reactors and feed vessels required.