Microwave technology offers rapid, selective, and efficient heating, making it a valuable tool for process intensification. In this context, this study employed microwave energy for rapid reaction optimization and reliable kinetic analysis for the catalytic conversion of glucose. Dehydration (DeH) and retro-aldol condensation (RAC) are two main routes for the catalytic conversion of glucose into valuable platform chemicals such as levulinic acid, methyl lactate, and other byproducts.

Bridging AI and self-driving laboratories, we introduce the first fully-automated, closed-loop molecular discovery cycle, exemplified by the identification of novel JAK inhibitors. With minimal human intervention, we combined AI-driven molecular design and retrosynthesis with IBM’s synthesis automation system RoboRXN and Arctoris’ Ulysses platform for automated in-vitro screening.

VDI news / nachrichten

Up to 220 paint samples per day go through a fully automated screening in a unique testing facility at Byk in Wesel. / Bis zu 220 Lackproben pro Tag durchlaufen ein vollautomatisches Screening in einer weltweit einmaligen Pruefanlage bei Byk in Wesel.

Selective hydrogenation plays a critical role in modern synthetic chemistry, particularly in the pharmaceutical industry, where the production of chiral molecules with high enantiomeric purity is essential for the efficacy and safety of active pharmaceutical ingredients (APIs). 

Mobile robotic chemists are a fast growing trend in the field of chemistry and materials research. However, so far these mobile robots lack workflow awareness skills. 

The integration of automated synthesis and machine learning (ML) is transforming analytical chemistry by enabling data-driven approaches to method development. Chromatographic column selection, a critical yet time-consuming step in separation science, stands to benefit substantially from such advances.

The development of a general autonomous platform for organic synthesis that enables faster, flexible and efficient delivery of target molecules is an attractive strategy for many fields such as drug discovery and material sciences.

We are proud to spotlight our partnership with Ames National Laboratory, a key leader in the U.S. Department of Energy’s historic Genesis Mission—an initiative harnessing the power of Artificial Intelligence (AI) to transform American science and innovation.

Herein, we describe the development of the high-throughput experimentation platform and function in AbbVie’s Discovery Chemistry organization.

Empa und internationale Partner haben den bislang größten offenen Batterie-Datensatz im neuen Battery Data Format (BDF) veröffentlicht.