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Automated tools to accelerate catalyst screening and discovery

July 4, 2023
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Canadian Chemistry Conference and Exhibition (CSC 2023) - Chemistry at the Edge 
Vancouver, June 4-8, 2023

Graham Lee, Weiling Chiu - NOVA Chemicals

Catalyst activation is an important aspect of polyolefin catalyst research and development. Here we describe a high-throughput catalyst activation strategy screen based on microscale 1-octene polymerization reactions (0.5 µmol catalyst per reaction). With this screen, hundreds of unique catalyst systems were evaluated using automated equipment. Results show that combinations of catalysts, co-catalysts, and scavengers with various chemical and structural properties can lead to dramatic changes in 1-octene polymerization performance. Importantly, several trends observed using this screen have also been described at larger scales.

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Source:

https://www.xcdsystem.com/cic/program/53nSuUT/index.cfm?pgid=2828&sid=26507&abid=99275

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