Villeneuve d’Ascq Cedex / Paris, France First catalytic asymmetric hydrogenation of quinoxaline-2-carboxylates “For the first time, the asymmetric hydrogenation of quinoxaline-2-carboxylates was performed successfully. The best catalysts are based on iridium complexes modified by chiral phosphorous ligands. Accelerated examination of ligands and catalysts has been undertaken by using a Chemspeed workstation, which enables carrying out, in parallel, eight independent catalytic reactions at the laboratory scale. Tetrahydroquinoxaline-2-carboxylates could be obtained with high yields and up to 74% ee.” 
For details: First catalytic asymmetric hydrogenation of quinoxaline-2-carboxylates Anna M. Maja,*, Svetlana Heyteb, Marcia Araqueb, Franck Dumeignilb,c, Sébastien Paulb, Isabelle Suissea,*, Francine Agbossou-Niedercorna,* a UCCS (Unité de Catalyse et de Chimie du Solide UMR 8181), CNRS, Université de Lille, ENSCL, Cité Scientifique, CS 90108, 59652 Villeneuve d’Ascq Cedex, France b UCCS (Unité de Catalyse et de Chimie du Solide UMR 8181), CNRS, Université de Lille, Ecole Centrale de Lille, Cité Scientifique, CS 20048, 59652 Villeneuve d’Ascq Cedex, France c Institut Universitaire de France, 103 Boulevard Saint-Michel, 75005 Paris, France * Corresponding authors Tetrahedron, Volume 72, Issue 10, 10 March 2016, Pages 1375–1380
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