Automated Intelligent Platforms for High‐Throughput Chemical Synthesis

Artificial Intelligence Chemistry

Automation and high-throughput techniques provide a solid technical foundation for realizing the deep fusion of artificial intelligence and chemistry as well as the full utilization of their advantages. In recent years, with the unique advantages of low consumption, low risk, high efficiency, high reproducibility, high flexibility and good versatility, intelligent automated platforms for high-throughput chemical synthesis aroused widespread concerns of synthetic chemists. In this review, the automated high-throughput chemical synthesis, automated high-throughput sample treatment and characterization technique, as well as the application of artificial intelligence technique in chemical synthesis are introduced. The characteristics of the systems and platforms based on these techniques, including the iChemFoundry platform developed in the ZJU-Hangzhou Global Scientific and Technological Innovation Center, are introduced. The intelligent automated platforms for high-throughput chemical synthesis will reshape the thinking mode of traditional disciplines, promote the innovation of disruptive techniques, redefine the rate of chemical synthesis, and innovate the way of material manufacturing.

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Automated Intelligent Platforms for High‐Throughput Chemical Synthesis

Jia-Min Lu a,b, Jian-Zhang Pan a,b, Yi-Ming Mo a,c, Qun Fang a,b

a. Engineering Research Center of Functional Materials Intelligent Manufacturing of Zhejiang Province, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Hangzhou 311200, China
b. Institute of Microanalytical Systems, Department of Chemistry, Zhejiang University, Hangzhou 310058, China
c. College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310058, China

DOI: https://doi.org/10.1016/j.aichem.2024.100057

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