example solution
Swing

Automated small-molecule reaction screening (μL to mL scale)

ISYNTH REACTSCREEN
Overview

Chemspeed's solution

Our overhead gravimetric (patented) dispensing of solids & liquids combined with our fully automated small-scale reactor formats (μL to mL scale) and our user-friendly software boost you to accelerate, standardize and digitize your small-molecule reaction screening (incl. reaction preparation, photochemistry, work-up, analysis). 


Workflow

Example workflow

ISYNTH REACTSCREEN

Benefits

Powerful advantages

  • Decrease in cost per experiment up to 90+ %.
  • Increase in productivity by a factor of 10+.
  • Easy-to-use disposable glass reactors / vials and / or reusable double-jacket reactors.
  • Small-scale synthesis at ambient pressure & up to 100 bar.
  • Enabled by SWILE (one-to-one / many-to-many gravimetric pick & dispense of solids).
  • Mixing by shaking or tumble stirring.
  • Reagent preparation (liquids and solids), multistep synthesis, work-up, purification, analysis and product transfer to storage.
  • Ventilated, conditioned hood for e.g. sensitive, low-temperature chemistry - 70 to 200 °C.
  • 4-Needle Head for volumetric liquid handling and sampling.
  • Gravimetric solid dispensing into an unlimited choice of vial / plate / reactor formats.
  • The balance moves to the destination, increasing speed and efficiency.
  • Balance resolution of 100 μg, or 10 μg.
  • A large dispensing range, from μg up to several g.
  • Powder dispensing / dosing robotic tool can be combined with other tools to accommodate multiple workflows.
  • Dispensed amount, mixing speed, temperature, time, ... and other data are stored in a read only log file.
  • Exchangeable robotic tools to accommodate multiple workflows.
  • AUTOSUITE SOFTWARE - drag & drop experimentation with easy interface to data analysis.
  • Interface to e.g. DOE, ML, AI, LIMS, ELN, ERP.
Software
Chemspeed AutoSuite Software laptop screen