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BioPACIFIC MIP Automated Chemistry Facility | Robotic High-throughput Polymer Synthesis

November 20, 2024
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BioPACIFIC MIP’s Synthetic Chemistry Facility strives to provide investigators with comprehensive synthetic chemistry capabilities as well as purification, analysis and quality control under one roof.

The NSF BioPACIFIC MIP operates a one of a kind user facility dedicated to creating a nexus for synthetic biology and materials to revolutionize high-performance polymers. Users are uniquely able to elucidate biomaterial structure and function to achieve materials-by-design, construct new bio-derived functional monomers from living organisms, access novel sequence-specific materials (e.g. peptoids), synthesize stimuli-responsive “smart” biomaterials, scale-up biomaterial production, and incorporate state-of-the-art theoretic simulation and machine learning algorithms.

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Aqueous sonochemical synthesis of covalent organic frameworks

Covalent organic frameworks (COFs) are versatile materials platforms for precise function integration owing to their high crystallinity, large surface areas, tunable characteristics and diverse and predictable structures. However, the dominant solvothermal method for COF synthesis requires harsh conditions, including high temperatures, toxic organic solvents, sealed and pressurized reactors, and extended reaction times that often exceed several days.

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