Agricultural and Food Chemistry
Mycotoxins are naturally occurring toxins produced by certain fungi. Exposure to mycotoxins may occur through the consumption of contaminated foods or from animals that are fed contaminated feed. To safeguard the nation’s food supply, the U.S. Food and Drug Administration (FDA) utilizes a comprehensive mycotoxin program which samples and analyzes foods for surveillance and compliance purposes, including enforcing action levels. Mycotoxin analysis is at the center of the mycotoxin program, as concentration data are needed for data analysis, scientific assessments, and risk management. This review focuses on the Agency’s continuous efforts to develop and incorporate fit-for-purpose analytical tools for mycotoxin analysis with particular focus on the relationship between analytical methodologies and scientific assessments. The discussion further highlights challenges and advancements in analytical methods and discusses future possibilities to develop analytical tools and preventative risk management approaches to meet the evolving regulatory needs.
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Kai Zhang, Brenna Flannery and Lauren Zhang
Food and Drug Administration, Center for Food Safety and Applied Nutrition, Office of Regulatory Science. 5001 Campus Drive, College Park, Maryland 20740, United States
DOI: https://pubs.acs.org/doi/10.1021/acs.jafc.4c01746
