Cu(0)-mediated polymerization of hydrophobic acrylates using high-throughput experimentation

Ghent University, Belgium

Polymer Chemistry Journal

In this paper the optimization of the Cu(0)-mediated polymerization of n-butyl acrylate and 2-methoxyethyl acrylate is reported using an automated parallel synthesizer. Using this robot, up to 16 kinetic reactions could be performed in parallel, resulting in a fast screening of different reaction conditions. Several parameters were optimized to determine the optimal reaction conditions with regard to control over the polymerization and reaction rate. These optimal reaction conditions were then used for the one-pot two-step synthesis of diblock copolymers by sequential monomer addition.

For details: Cu(0)-mediated polymerization of hydrophobic acrylates using high-throughput experimentation

Lenny Voorhaar,ac Sofie Wallyn,b Filip E. Du Prezb and Richard Hoogenboom*a

a.) Supramolecular Chemistry Group, Department of Organic Chemistry, Ghent University, Krijgslaan 281 S4, B-9000 Ghent, Belgium.

b.) Polymer Chemistry Research Group, Department of Organic Chemistry, Ghent University, Krijgslaan 281 S4 Bis, B-9000 Ghent, Belgium

c.) SIM vzw, Technologiepark 935, B-9052 Zwijnaarde, Belgium

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Polymer Chemistry
DOI: 10.1039/c4py00239c
www.rsc.org/polymers
The Royal Society of Chemistry

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