Continuous Flow Synthesis of Diglycolamides for Rare-Earth Elements Recovery: Algorithm-Accelerated Reaction Optimization Coupled with Automated Extraction Evaluation
A first example of diglycolamide flow synthesis was developed, showcasing algorithm-accelerated reaction optimization and its potential to accelerate ligand discovery and enable autonomous, AIcontrolled manufacturing of critical materials. The increasing demand for manufacturing rare-earth elements (REEs) as critical materials has intensified research on sustainable synthesis of advanced extractants such as diglycolamides (DGAs).
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