Synthesis of Novel Bromodifluoromethyl(arylsulfonyl) Compounds and Nickel Catalyzed Cross Coupling with Arylboronic Acids

{"style":"unordered","items":[{"content":"Prepared two novel bromodifluoromethyl(arylsulfonyl) compounds","items":[]},{"content":"Using high-throughput experimentation (HTE) we have identified a very challenging Suzuki type coupling reaction catalyzed by nickel, providing direct formation of C_sp2-CF₂SO₂Ar bonds","items":[]},{"content":"We propose a CF₂SO₂Ar radical species is involved in the reaction pathway","items":[]},{"content":"Future work will focus on the use of a photocatalyst to improve the harsh conditions of this transformation","items":[]}]}