Solutions for Pharma R&D and QC
Boost the diversity, output and quality of your pharma R&D with automation and digitalization designed by chemists for chemists.
Accelerating your existing workflow
The pharmaceutical industry faces the increased demand for innovative, better, “rule of five compatible” medicines against various diseases.
Time-to-market of easily accessible and at the same time highly innovative API’s is essential.
Chemspeed provides high throughput and high output solutions which accelerate, standardize and digitalize your R&D and quality control without compromise in areas such as:
- Versatile gravimetric solid dispensing and liquid dispensing from microg-to-mg-to-g for sample, synthesis, formulation preparation
- Sample preparation in e.g. analytics, QC, compound management
- Library synthesis with diverse synthesis methodologies in drug discovery / medicinal chemistry / hit-to-lead optimization
- Reaction screening in lead optimization / late stage drug discovery
- Route scouting and process / chemical development
- Formulation screening and development of solid and liquid forms (e.g. polymorph screening, excipient compatibility screening, stability screening, nanoformulations with controlled release properties)
- AI supported knowledge evolution
- Individualized production
Highly innovative technologies allow mimicking virtually any workflow in a fully automated way. This saves precious time and increases diversity, output and quality of your lab dramatically by using concepts designed for chemists by chemists.
Pharma example solutions
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High throughput peptide, oligonucleotide and oligosaccharide synthesis
Molecular diversity / large-molecule discovery in e.g. medicinal chemistry enabled by our high throughput library synthesis solutions in disposable glass vials and / or reusable double-jacket reactors and / or microwave reactors and / or photochemical glass reactors. The leading technology in overhead gravimetric dispensing / dosing (patented) combined with our disposable glass reactors, and our user-friendly software, allow you to accelerate, standardize and digitalize your (oligo)peptide, (oligo)nucleotide and (oligo)saccharide workflows.
Automated versatile gravimetric solid dispensing
Chemspeed's FLEX POWDERDOSE with its proprietary overhead gravimetric solid dispensing / dosing (mg to g) and our user-friendly software allow you to automatically dispense virtually any powder / solid and extrudate into any type of destination.
Versatile solid reagent filling
Chemspeed's FLEX POWDERDOSE for versatile solid reagent filling into a vast range of recipients enabled by our unique overhead gravimetric dispensing of solids and automated decapping / capping.
Automated versatile gravimetric solid dispensing
Automated gravimetric solid dispensing / dosing - precision, accuracy, speed, data integrity (incl. applications in GMP environments).
Versatile matrix-to-matrix gravimetric pick & decision dispense of solids
Gravimetric pick & decision dispense of solids (matrix-to-matrix) - paradigm shift in solid / powder distribution / reformatting.
End-to-end DSC sample preparation
Step-change in end-to-end DSC sample preparation - gravimetric pick & decision dispense of solids / matrix-to-matrix reformatting.
End-to-end NMR and LCMS sample preparation
Step-change in end-to-end NMR and LCMS sample preparation - gravimetric pick & decision dispense of solids / matrix-to-matrix reformatting, dissolution and online / offline NMR and / or LC-MS (incl. applications in GMP environments).
Matrix-to-matrix gravimetric pick & dispense of solids for catalyst screening
Paradigm shift in catalyst screening - gravimetric pick & dispense of ligands, catalyst precursors, catalysts.
Mother-to-daughter gravimetric pick & dispense of solids
Step-change in solid compound management - gravimetric pick & dispense of solids for e.g. biological screening.
Fractional compositional mapping by gravimetric pick & dispense of solids
Formulation screening enabled by fractional compositional mapping based on gravimetric pick & decision dispense of solids.
Pharma news
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High-throughput solid microsampling through stochastic robotic automation
Solid sampling at the sub-milligram and milligram scale remains a major bottleneck for high-throughput chemistry or material sciences, as existing approaches rely on manual handling or slow deterministic microsampling that do not readily scale. Here we present STORMS, an automated STOchastic Robotic MicroSampling system that enables fast, reliable and parallel sampling of solid materials at sub-milligram and milligram masses.
Integration of Machine Learning and Automated Synthesis for Accelerated Drug and Material Research
The challenges posed by global climate change and disease risks have intensified the demand for efficient and practical materials and molecules. Traditional trial-and-error approaches are becoming increasingly inefficient and resource-intensive. The rapid advancement of artificial intelligence (AI) has opened new avenues to accelerate research and shorten development cycles.
Localization, inspection, and reasoning (LIRA) module for autonomous workflows in self-driving laboratories
Self-driving labs (SDLs) combine robotic automation with artificial intelligence (AI) to allow autonomous, high-throughput experimentation. However, robot manipulation in most SDL workflows operates in an open-loop manner, lacking real-time error detection and error correction. This can reduce reliability and overall efficiency.
An Automation Platform for the Chemoenzymatic Synthesis of Complex Sulfated and Branched Glycans
Diverse collections of well-defined glycans are needed to investigate the molecular mechanisms by which these biomolecules mediate biological and disease processes. Several automation approaches have been introduced to accelerate the enzymatic synthesis of complex glycans. These methodologies have, however, provided only relatively simple oligosaccharides due to limitations of glycosyl transferase selectivity.
Implementation of Large-Scale Multi-Reactor Automation for Process Development
Pharmaceuticals increasing complexity requires longer synthesis with unique processes for each step, increasing the number of experiments to develop robust sustainable processes. The time to develop these processes is getting shorter, and automation can support the growing need to efficiently perform more experiments.
synTQ: The Intelligence Layer Powering Automated QC and Smart Manufacturing
In modern pharmaceutical and bioprocess manufacturing environments, automation alone is no longer enough. True digital transformation requires every instrument, robot, sensor, and workflow to operate with precision, reliability, and complete data integrity.
Start Your Journey With Chemspeed
From innovation to quality, Chemspeed delivers automation & digitalization that grows with your lab.
Chemspeed is a global team committed to enable automated and digitalized workflows for scientists in R&D and QC.
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