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Automated active ingredients (AI) library synthesis

ISYNTH AI
Molecular diversity / molecule discovery in e.g. medicinal chemistry enabled by our high throughput library synthesis solutions in disposable glass vials and / or reusable double-jacket reactors and / or microwave reactors and / or photochemical glass reactors.
Overview

Chemspeed's solution

The leading technology in overhead gravimetric dispensing / dosing (patented) combined with our disposable or reusable or microwave or photochemistry reactors and our user-friendly software enable you to accelerate, standardize and digitize your parallel library synthesis / work-up / analysis workflows for enabling your innovative medicine R&D. 

Chemspeed’s ISYNTH deck modularity provides unrivalled versatility to execute and perform a variety of workflows in a fully automated fashion, including reaction preparation, multistep synthesis, work-up, purification, analysis and product transfer to storage.

Workflow

Example workflow

The interactive workflow panel below showcases example workflows for this solution. Each Chemspeed tool or module performs a set of specific actions, as in any manual lab workflow, and an almost limitless arrangement of these tools is possible.

ISYNTH AI

Details
đź’ˇ Click on a workflow node to see more details in this details panel.
Benefits

Powerful advantages

  • Decrease in cost per experiment up to 90+ %.
  • Increase in productivity by a factor of 10+.
  • Easy-to-use disposable glass reactors / vials and / or reusable double-jacket reactors and / or microwave and / or photochem reactors.
  • Reagent preparation (liquids and solids), multistep synthesis, work-up, purification, analysis and product transfer to storage.
  • Ventilated, conditioned hood for e.g. sensitive, low-temperature chemistry
  • - 70 to 200 °C.
  • 4-Needle Head for volumetric liquid handling and sampling.
  • Gravimetric solid dispensing into an unlimited choice of vial / plate / reactor formats.
  • The balance moves to the destination, increasing speed and efficiency.
  • Balance resolution of 100 μg or 10 μg.
  • A large dispensing range from μg up to g.
  • Powder dispensing / dosing robotic tool can be combined with other tools to accommodate multiple workflows.
  • Dispensed amount, mixing speed, temperature, pressure, time, ... and other data are stored in a read only log file.
  • Various integrated analytics such as HPLC (MS), UPLC (MS), GC (MS), Online benchtop flow-cell NMR, offline benchtop NMR.
  • Additional integrated analytics, including online benchtop flow-cell UV-VIS, pH measuremnt & adjustment, NIR & MIR measurement cell and DLS measurement cell.
  • Exchangeable robotic tools to accommodate multiple workflows.
  • AUTOSUITE SOFTWARE - drag & drop experimentation with easy interface to data analysis.
  • Interface to e.g. DOE, ML, AI, LIMS, ELN, ERP.
Software

AUTOSUITE

Chemspeed’s AUTOSUITE software packages execute and control all modules in every solution. They control all Chemspeed robotic platforms and any other integrated 3rd-party software and hardware.

Explore AUTOSUITE
Chemspeed AutoSuite Software laptop screen
Automate and digitalize your laboratory with Chemspeed.