example solution

Matrix-to-matrix gravimetric pick & dispense of solids for catalyst screening

FLEX SWILE catalyst screening

Chemspeed's solution

Ligand, catalyst precursor and catalyst distribution / reformatting from the libraries into reaction screening plates is often still done manually and binds highly qualified resources to very time-consuming, tedious, and error-prone tasks. 

The SWILE technology provides fully automated true one-to-one gravimetric "pick & decision dispense" of catalysts. The scheme at the bottom of this page displays the simplified SWILE workflow including the precision "pick & decision dispense" step. The technology backbone is following Chemspeed’s proprietary overhead gravimetric dispensing tool design in combination with a second analytical on-deck-balance. 

In order to exclude any risk of cross-contamination disposable glass tips are used which are stored and provided by the SWIN dispenser. The SWINs are available in different sizes (diameter) and can be adjusted according to the desired target amount to be dispensed. Additionally, a tilt / shake rack is used to loosening up and tilting the solid prior to pick-up.

  • Revolutionary accuracy & precision due to decision dispensing
  • Dispensing range from <100 μg to about 5 mg with +/- 10 μg resolution
  • No cross-contamination
  • No dead volume
  • Unattended operation
  • Fully inert (glass)


Example workflow

FLEX SWILE catalyst screening


Powerful advantages

  • Proprietary robotic tool exchange interface.
  • Ventilated hood for safety and conditioned operation, trolley.
  • SWILE Robotic Tool can be combined with other tools to accommodate multiple workflows, e.g. small-scale reactor for subsequent μL reaction screening.
  • On-deck balance, tilt / shake rack, barcode reader, multigripper.
  • AUTOSUITE SOFTWARE - drag & drop experimentation with easy interface to data analysis.
  • Interface to e.g. DOE, ML, AI, LIMS, ELN, ERP.
  • Optimized footprint (3x3 ft, 90x90 cm) versus capacity - all while reducing costs and maximizing return on investment.
Chemspeed AutoSuite Software laptop screen