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Data science-driven autonomous reaction optimization by UBC, Merck Co., Inc. and Chemspeed

November 12, 2020

Data driven high-throughput experimentation is enabling accelerated screening within pharmaceutical companies. New data science tools combined with machine learning are being implemented to efficiently tackle multivariate reaction optimization challenges.

Melodie Christensen, from Merck & Co., Inc., and UBC provide an overview of the use of automation in her Data Rich Experimentation (DRE) lab and her move towards autonomous reaction screening in conjunction with digitalization.

Melodie is an Associate Principal Scientist, Merck & Co., Inc. and a Ph.D. student at the Department of Chemistry, the University of British Columbia.

She has a proven track record in high-throughput experimentation platforms to support early and late stage pharmaceutical process development.

Webinar

For more information about Chemspeed solutions:

SWING RP

FLEX ISYNTH

ISYNTH REACTSCREEN

For details please contact [email protected]

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Read more about High-throughput solid microsampling through stochastic robotic automation
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High-throughput solid microsampling through stochastic robotic automation

Solid sampling at the sub-milligram and milligram scale remains a major bottleneck for high-throughput chemistry or material sciences, as existing approaches rely on manual handling or slow deterministic microsampling that do not readily scale.

Here we present STORMS, an automated STOchastic Robotic MicroSampling system that enables fast, reliable and parallel sampling of solid materials at sub-milligram and milligram masses. 

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